“These must be answered before designing, or attempting to design, treatments for neurodegenerative diseases. “It could be a matter of finding dividing lines - how much coffee is preventative and how much is harmful,” Dr. “For example,” he told us, “causation has not yet been established - other studies have shown that drinking coffee an increased risk of dementia.” Joel Salinas, a neurologist at NYU Langone Health, not involved in the study, pointed out that this is very early research, and several other areas of investigation need to be explored. Nevertheless, the researchers who conducted the current study say that their preliminary in vitro findings could pave the way toward finding or designing other bioactive compounds against neurodegenerative diseases, including Alzheimer’s.ĭr. “ Antioxidant substances that claim to be neuroprotective are plentiful,” Segil told MNT, “and in theory, they may actually be healthy, but claims coffee brew is going to protect someone from getting a neurodegenerative disease is challenging to agree has scientific merit.” However, antioxidants alone are unlikely to offer full protection against any disease or health condition. That may be because antioxidants from a person’s diet can help protect against cellular aging. It may also have beneficial effects on brain health. “No medication affecting tau structure shown any clinical benefits to clinical neurologists like me who treat patients with neurodegenerative diseases like Alzheimer’s dementia or Parkinson’s disease,” Segil cautioned.Ĭould antioxidants protect against dementia?Ĭoffee is a source of antioxidants in the form of polyphenols, which has led some researchers to suggest that it can bring various health benefits including lowering the risk of type 2 diabetes and some forms of cancer. “Unfortunately, many modern neuroscientists believe these tau proteins may be more akin to freckles, which are most often normal aging pigments, rather than an accumulation that causes neurological disease,” he noted. Remember that constipation refers to having fewer than three bowel movements per week, even though how often a person 'goes' varies widely, per the Cleveland Clinic. However, Segil also noted that it is unclear whether the study findings will actually lead to a new therapeutic strategy against neurodegenerative conditions. In some situations, caffeine can actually relieve or prevent constipation, Dr. The goal is to design a therapy for these diseases using a coffee brew extract base.” In the present study, adding coffee brew to a simple form of the tau protein prevented the tau protein from aggregating, condensing, and seeding activity. “Tau is present in patients with Alzheimer’s dementia and Parkinson’s disease. “ noted that, in test tubes, adding coffee brew to a protein called tau, made the tau protein stop from forming into something that has been shown to present in neurological diseases which cause memory loss and shaking,” Segil told Medical News Today.
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